Acebutololand Its Metabolitesin Determinationsof Urinary Metanephrines

CLINICAL CHEMISTRY, Vol. 28, No. 5, 1982 1243 to have concentrations for all the above that were within the normal range. FPG, TG, TC, and UA were measured with the SMA-12 Technicon multi-channel analyzer; HDL-C was measured by the method outlined in the Lipid Research Clinics Manual of Laboratory Operations (6). The intercorrelations are shown in Table 1. The fact that significant correlation coefficients exist between the above metabolic variables does not prove that they are causally related. However, the measurement of any one of them may be a useful indicator of the presence of another “latent” abnormality. For example, of 18 individuals with a HDL-C of <0.4 g/L, 12 (66%) had a FPG >1 g/L. Only four of 33 subjects with a HDL-C of >0.6 g/L had a FPG of >1 g/L. Conversely, 36 of 45 men with a FPG of >1 g/L had an HDL-C of <0.5 gIL, and 37 of 46 men with a FPG of <1.OgIL had an HDL-C of >0.5 gIL.